For those keeping track of IANA's IPv4 /8 delegations to the Regional Internet Registries (RIR) the final blocks 2 /8's have been assigned, 39/8 and 106/8 went to APNIC. You can see the IANA IPv4 Address Space Registry for details of how things are delegated out not that it will help much but it is interesting to see some of the Legacy allocations.
So the next 5 /8's will be allocated automatically here shortly - guess IANA wanted to do that slower then all at once with the other 2 /8's going out to APNIC. So that is it - IPv4 address space is officially exhausted.
From a practical perspective not a lot will change until the RIR's start running out of address block. The rates will vary for each RIR and Stephen Lagerholm has a great blog on the run rates and what the timing likely will be until they have no IPv4 addresses to hand out anymore.
So what will everyone do once that happens? Luckily the Answer to the Ultimate Question of Life, the Universe and Everything is 42... or is it 2^128?